4-AcO-DMT: The Synthetic Psilocybin Analog – Research & Effects
What Is 4-AcO-DMT?
4-AcO-DMT (4-Acetoxy-N,N-dimethyltryptamine) is a synthetic psychedelic compound closely related to psilocin, the active metabolite in magic mushrooms. Developed by Albert Hofmann (inventor of LSD) in the 1960s, it was initially studied alongside other tryptamines before being shelved. Buy 4-Aco DMT
Key Facts:
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Prodrug to Psilocin: Converts into psilocin in the body, producing near-identical effects.
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Legal Status: Unregulated in some countries but illegal under analog laws in others (e.g., U.S. Federal Analog Act).
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Forms: Typically found as a white/brown powder or in capsules.
4-AcO-DMT vs. Psilocybin Mushrooms: How Do They Compare?
Feature | 4-AcO-DMT | Psilocybin Mushrooms |
---|---|---|
Onset | 15-45 min (oral) | 30-60 min |
Duration | 4-6 hours | 6-8 hours |
Potency | More consistent (pure compound) | Variable (natural fungi) |
Effects | Nearly identical, but some report smoother come-up | More body load/nausea |
Potential Therapeutic Benefits (Based on Anecdotal & Preclinical Data)
While no clinical trials exist, user reports and pharmacological similarities suggest:
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Depression & Anxiety Relief (similar to psilocybin therapy)
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Neuroplasticity Effects (may promote brain connectivity changes)
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PTSD & Addiction Research Potential
⚠️ Caution: Lack of regulation means dosage accuracy, contaminants, and safety risks are concerns. Buy 4-Aco DMT
4-AcO-DMT Dosage Guide
Due to its potency, dosing must be precise:
Dose Range | Effects |
---|---|
1-5 mg | Microdose (sub-perceptual) |
10-20 mg | Mild visuals, mood lift |
20-30 mg | Full psychedelic experience |
30+ mg | Intense, DMT-like effects |
The recommended dosage of 4-AcO-DMT varies, generally ranging from 10 to 30 mg. A 20 mg dose is often considered equivalent to approximately 3 grams of dried psilocybin mushrooms. For those new to 4-AcO-DMT, starting with a lower dose and gradually increasing is advisable.
Harm Reduction Tips:
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Start low (10-15 mg for beginners).
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Use a milligram scale—volumetric dosing recommended.
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Avoid mixing with MAOIs, SSRIs, or stimulants.
Risks & Safety Concerns
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Psychological Distress: High doses may trigger anxiety/panic.
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Legal Risks: Banned in many countries under analog laws.
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Unknown Long-Term Effects: No studies on chronic use.
Alternatives to 4-AcO-DMT
For legal options, consider:
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Psilocybin therapy (where decriminalized)
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Ketamine clinics (for depression)
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Lion’s Mane mushrooms (neurogenesis support)
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